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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48c68a11b4ad627af61e60a0840b7d664578c04bf9130bbf6bc4fc8396ba6271' 
  AND token = 'kumLm+1c15cPap+vqOF+U5TDboz1IGFk2Z4W31KVc7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}