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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7def335d115b11c235a235d84aa03f6dc2501978792964f188b6325f58e4e4' 
  AND token = '9v+ldb7qW0lf5Ql041SCvMte7PnexAZtiklYloe3XtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}