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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20163d197e20bca55b78f932463b6d6c62674de3f3a9577e7fd2bcb3f82e5b65' 
  AND token = 'P9LMGgCF/jgCx/5uC/4OuYEsEynjMeJ1nqeXb8CDNO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}