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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5952def8c60415faea6a051ff6f95ff3605ebeed8499171683353b2c3e029d' 
  AND token = 'kkRs70p39C80gok0iE2xLrPE201kUKbh1LwtyO+crIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}