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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9d4064ff5703ea6e8bde0b2eaa475af38ca01a1c458c640a0de19d1a3a71252' 
  AND token = 'XNBeisYhbbFGj1V3abiLIaxoOry6bG0mG56sYeZjHUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}