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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b947946d03c8b004fceee925d2864434cb160d6896cbc226dc15cf57f2da4e1' 
  AND token = 'v2Cj5wd3P9+6VojSt80Gexqs7MFUgWtQZtVUD0AifX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}