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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53d182a1e8562a2d10b6d5e08369680999b072924722bd70ab58016aff071ea' 
  AND token = 'GwYCSpQVMJq7k9y4ud7U6+uWkHaKC3stP9Y8OlOCivY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}