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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9af3d3e4c513dbbdfb2bf0ebdbcaafb25d191456b6482fcc5197366cb7115a88' 
  AND token = 'NyXMU2FozsbjW5xo+JwocTY1R32BIPSw+JA3pcp3Zcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}