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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8afbfaedbd92f79c189f919d72c58ca3db259989d4b651010333f0d3a927203e' 
  AND token = '4SJ846Bjn+d+TxbCua1fqCCe8M+FggUINDICCpGYHY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}