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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5ffc063c1506c94f5e5ca42cbe6f967aee1d750d05b3aba779073a42eecff2b' 
  AND token = '0+ResuQEYC4MnUFDhv3PIWqeFLd23VIQzgujOCFoc00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}