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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3748852ecc016bec9a212bdb26faff788cf5789773f41322149e8329100343af' 
  AND token = 'm0sU5lknOJgAb3SU9kPHAhcZxxbGDJ37TsgWmi6WqU8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}