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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68cc21046b128115d3d4859aac83d3984a3546038df344b420017089f500cf54' 
  AND token = 'fz/f+AhSshPEU08aBW84/TiSGJO4vEVXsSTSSrszrbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}