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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed16dbb44efea2500cb89459ee749c073b9e0da3c55bfa92f01f4cc9ca31ac4' 
  AND token = 'oHERUkf4jz4x/eE822l3RC+sfRhfFwGCIeXZY0djgN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}