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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dedc5f70d8e765e0f3ff25ef89321e425bf9687fb8c007a66391d09bf1f64812' 
  AND token = 'owxI2qxRD6ZS+N9gq29rTFBN2yRquK29oM/E70z1M9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}