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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0a9f891ad39bd2a50f90cd9b8f9aa0df761d42520cfe3e6bf3fbee7b80fcab6' 
  AND token = 'CrhliL/p9Xdkx/teJuhQoJNQ4MyVR7CmqMrG2rbtdcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}