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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34b3271ce3af0222628483f1808cf5f205b9a4255ca7b4f1990ab007580bf327' 
  AND token = '2uGpsLgRuKg3ngKkfzuvjeiURYLGHnMOA/wfEei8IKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}