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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5965c4144b399dd9dca5f328e5c1b9abfbc9a264c5be6f776dfb55a2a470905b' 
  AND token = 'ds0z0Y1Xk+Qcpm8bgv/bT7keXsn6ti7HyPk79FpkgPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}