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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4dede9e1c3b10ebe14d0a8d6897c738c04f183fdde45aeaaf9b3509d4d4e5d9' 
  AND token = 'XGXvIpLOpanXAjq4VTkiBiKjhDfUph1LT9LlHfbPBy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}