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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05555e179a1a6600510ac384c590e36451e652f1ffcae25d4f01702a32bb61be' 
  AND token = '4mCQZPHThb/WKG/yeLKeJpDXT09S0DdNaI4eXGZ+fuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}