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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2be615ae1b98b49c82c65a4299b66ad527b194131a2f89957f52b77e3ca3dbe' 
  AND token = 'A3mDOCNNV18MpppZj/b5lnXSpN3qveZlom7rWQmhx8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}