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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7517c7080adef616b3b11764037a4c0cd7c3ba31988b8af6226057f72cbd6955' 
  AND token = 'A91Orw9e82T2GBk+ZF+hB1gzm6d9sZrBDepkCzTBDp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}