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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493ecb7bfb4f65d2bddda20bbdf2f6b4dfefecef0476b78c0e527157b1295118' 
  AND token = 'Cf7JTjoEATK1MZjjbWJiIQ7HgRKFgW9/vvINHAIS1kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}