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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecc817b3005f860b1947388c89782fbe72bd7d004940960cd1988d595c3fbc35' 
  AND token = 'nQ5ds/KEY4f6px+2DWWUg3TFgsZCLg+O6SzDD+0WRfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}