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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f633ffb1b50e0f8b601f0fcb8f96b1c5869f8a20da5be546a34f2290fffb7d6' 
  AND token = 'x9o7q7Lg82e9M8FukPFDnqfuxJ3PmnpIz7BrpB8EAlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}