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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c8b5c0a880fdc66d825c14344fc3981af1124cadad222a32e1da8ddc36631b3' 
  AND token = 'sCf/t3PFxnOKx5DExB9+Q5xnadBc7WmdKKsCmn4m/aY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}