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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dce5ed6bd6e130bde08e629c1d38feaf8631e1e77dff57e96c691e999cc366f2' 
  AND token = 'h8FLnL8hw9Ss7aHJwZeLhRYAlyxhffJ/5y1lkVGLu1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}