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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7e8fffa11cbad13921d1d5c49167074632909f05f596f68070ba11c9e5fdbb1' 
  AND token = 'O2FdZFNNrYd1v/WSOm/wKA5o9oRVjoOEynHQJGmyiwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}