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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cf9c2b0fe3251997b26d9a709c6cea6b6fd64e53ae6fed4c5b54101d2ac140' 
  AND token = 'WzuIDqLo2jb7Ti6wcDtFt4wcOyY+3z0ySIwplDwK0eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}