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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23ccef025c0d0314f835daed60a60e36d1786d50ee802f1016e6798207a5baa2' 
  AND token = 'LqDW13yayHc0hdBuM/Vsv5NiHCBw1NTkor9Fb/5nfcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}