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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed65c0eaf33c8caa4ef4fb1a526d22dcbb6dfbe05f94d4a1d99d1349c20b8495' 
  AND token = 'BJ6E3zpwhPwrY2SYNAk2cbp7jXSjeQY4dtG+cHgIVHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}