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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee28fcd721feb286d245f2021cdd5019d508257b494e5e79f2f633b233bcf9d9' 
  AND token = 'pNJejmx3trSDcC547lMMpxfsNynmo9QGYsFbsYlGbnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}