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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0833a1f66a182b06d9b8fe429404566c36d2e52c5e94de7a871d1a54d02a7b6' 
  AND token = '21ftjXf5U7Cx46lmlLX0oc/SbMGTgSAerZUiE+vFXvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}