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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e7df1459b788f8e9db18021dd529a53992c74effa1ee7d380c28fbc4f4d691' 
  AND token = 'a/ONnIoVwwBd2rp3RDpArMp8bz5rr4iDX3qKTMVVKdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}