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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67e44a39f26c75f711536007a0d4f4f60195dad3d5f1839178f1d206aa4bb943' 
  AND token = 'gzGE07DJGmXQFeH0Hn3QZ1RA7I0tbwNI6wd7rxKhERc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}