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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b049f4337549cffa434beb2d0e2a0c184a525d4023b303520e46932d2e28990e' 
  AND token = 'loW+nPa0MOsZcDQ58oquaCXm5WfsmxNyLNIqy8frabc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}