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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0ffdac2badd9f3e24e6a573f36e52a54bb478965504c9162a079e84cb0b3b20' 
  AND token = 'E/XQf1ASO4erQGuKmP6MhY4ohEelIPsHD+eRCoF+y9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}