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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4169cbe806c93958ca6bb7438927f121b6156ed359319caa938bdf7f4db9d533' 
  AND token = '80C/XkJzX+q2+7eJV577UFzvULa9gc8942CvSRYopcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}