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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea4be436a645c9bde2a2a330d88d6b77bbd3f04d5efdb501c13cf0907b1abc69' 
  AND token = '+WQSRlUs/vxIRU2R+pY7zfpHxgmWMSDkMwe/KmrERDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}