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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd07a129beecb90a1fcefa0dd7817f27565dc4365d93bf1c373e42625f534c3e' 
  AND token = 'PQfl1TSLoHMOB6RHqAg8/47CtASUXzqkvZKROBndZIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}