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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c93c1b14d588fd29e158619f79867c7b7704f46b2247abc421a6a1ff53ee500' 
  AND token = 'zVfYin3gEErRKYXA7sgNH+T3f8RUMu9YQRjdRWFq3eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}