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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bc217ebf311d1832960d114a3f117bb1cce1ae6931f1424a96d8aeabdff575f' 
  AND token = 'yYb3BmV5+24xU1ziBrjM0Nf34sCrzE77vUNHnS6+gKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}