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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd6a7be2dc433a4bd2e69e6a4577be29ff6b677ead365b67e8961dffae473975' 
  AND token = 'am/FeoJTuQVYhY7wZXkxaw6q4Birl9Kxtc/HQFVbYM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}