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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8866e78d712fdd0713d834ab3b7e0589d8512160fafed4b97697e4fe6f1d20c3' 
  AND token = '1oUWC69RLE0qK5NzEhvm1UfeXSf1Y4ejeq6xZRSBHvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}