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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd40851ce371021f1d5034a76df207636b59e255c01141b03441380c6729f9d40' 
  AND token = '42UTdYabS7to9gVLu6phzMjEo+ABZmqEqZ1s5E+ZWiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}