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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b21b184ca9eb1cc30754de6de571aa51136b6320d930727aa45ea2d2d8f965' 
  AND token = '7L3xDRcXY8hCQeNukkP3B9vypzYYJetZIIPB4ZyGLK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}