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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51bcb8289cf828abacdf40deebfcf983eee71c28de282c19f6b96d8b28c3c7a4' 
  AND token = '9w/nqHrXVOHryWgqQynCEXcQJTQN3d07b8aZ8kz6lC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}