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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd8844303d8f6f9d6b8dd6e0f6421d62993ff5e001bed2b0c0de0d8dd4ef60a8' 
  AND token = 'hkFY9SBt0HR4MXfW6DXlMz++CvqPShmh0VjjdIFJkEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}