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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9e0ed478bc0e42356e331a88c7d7392e454bab389b2d141eb633e5a2f3af330' 
  AND token = 'iYA5OxrrnzpLlLbaChUT4G7KqLLco3qoLzhNiNMrCco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}