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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbca17b033e7dd758536bc6b3f61d6d849257aaffaa3f0588d6d18446c31a9a2' 
  AND token = 'wEmyrV3mdGxF8cWtg467CVt+9eE1iV/fzRjhZfDbbdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}