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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8de5b41ed03069fd86e3a901a6ca1714aba1b0c662d23c22351988e237c946' 
  AND token = 'JP4W2+753KI3OsZbzzYUUWqUstIe4wtekxhEZLzZN7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}